不良研究所

不良研究所 Boston professor part of $3.8M grant to increase HIV testing, PrEP use

Nearly 40 years into the HIV epidemic, the  finds there are still about 40,000 new infections a year. Three-quarters of new infections are discovered in people of color and two-thirds are in sexual minority (gay and bisexual) men. Professor of Psychology  has made it his life鈥檚 work to be part of the public health response to the virus. He鈥檚 been working to develop interventions to get sexual minority men, especially black and Latino men, tested and treated for HIV.

鈥淭he way you think about the different health behaviors鈥攚e call it the 鈥楬IV cascade鈥欌攊t鈥檚 testing, learning about test results, engaging with care if a person is HIV-positive, starting medicine, maintaining themselves on medicine for a long period of time, and then having the virus be suppressed at a level where the person can live a normal life,鈥 Pantalone said.

Much of his recent work has been helping people living with HIV to take their medications and stay engaged with medical care, after beginning his research career focused on HIV prevention. Now, he鈥檚 shifting back to HIV prevention, given recent advances in that area. Pantalone is the clinical psychologist on a new 5-year $3.8 million National Institute of Mental Health (NIMH) grant designed to get Latino gay and bisexual men to be tested regularly for HIV and to take pre-exposure prophyaxis (PrEP), a medication treatment that prevents HIV acquisition. 不良研究所 Boston鈥檚 part of the grant is $228,000.

鈥淭he problem is there are lots of people at risk for infection who aren鈥檛 tested, and then people who are tested but who aren鈥檛 tested regularly enough. Every sexually active person should be tested for HIV and other STIs every six months,鈥 Pantalone said. Most new infections are the result of HIV transmission from people who don鈥檛 even know they are infected.

Pantalone, the graduate program director for  since 2015, has been researching and creating interventions related to the HIV epidemic in the U.S. since 2000 (he鈥檚 been on faculty at 不良研究所 Boston since 2012). This grant is one of seven federally funded projects which he is currently helping to lead.

With the new NIMH grant, Pantalone is again working with principal investigator , a senior behavioral scientist at the RAND Corporation, a private nonprofit based in Santa Monica. Bogart is an expert on community-based participatory research (CBPR), in which you engage closely with community members and use their input to help design the intervention. In this type of intervention development, the project is conducted 鈥榳ith鈥 the community rather than 鈥榦n鈥 the community.

鈥淢y job is to make the intervention work鈥攚rite a manual, hire and train a staff, and then listen to audio recordings of the sessions and do clinical supervision, to make sure that the therapy that they鈥檙e delivering stays within the bounds that we鈥檙e hoping for鈥攁nd the idea there is that our work is replicable, so we can say to an agency that we have evidence that says that this program is helpful鈥攚e recommend that you use this for your clients,鈥 Pantalone said.

Before this grant, Bogart, Pantalone, and others were part of a 3-year CBPR project called Still Climbin鈥 in which they worked to increase engagement with care and medication adherence among Black HIV positive, sexual minority (gay and bisexual) men. As published last year in Cultural Diversity and Ethnic Minority Psychology, the intervention worked, so the researchers partnered with Bienestar, a Latino-serving human services organization in Los Angeles, to see if the intervention might be helpful in another population at high risk for HIV.

鈥淔or the Black HIV positive, sexual minority men, 鈥 there was a lot of focus on the police, the government, and just in general, because of a legacy of medical mistrust that results from the Tuskegee syphilis experiment and other elements like that where the government did research that harmed people instead of helping them, especially Black Americans in the U.S. South,鈥 Pantalone said. 鈥淔or the Latino men, some of the issues are similar but the medical mistrust piece seemed less salient for them. [They are more concerned with] immigration and bias from health care providers because of being monolingual Spanish speaking or speaking with an accent, or because of their nationality or visa status.

鈥淥ur model is that discrimination experiences happen, and then they are a stressor for folks and then the discrimination experiences and the stress that results from them prevent people from engaging with the health care system, so we鈥檙e trying to find ways to reduce these barriers to care.鈥